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Symbol Name ID |
Dusp22
dual specificity phosphatase 22 MGI:1915926 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | decreased B cell proliferation |
increased T cell proliferation |
enlarged spleen |
increased spleen white pulp amount |
abnormal B cell activation |
decreased IgG3 level |
decreased IgM level |
decreased immunoglobulin level |
abnormal T cell activation |
increased circulating interferon-gamma level |
increased circulating interleukin-17 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
abnormal cytokine level |
increased interferon-gamma secretion |
increased interleukin-17 secretion |
increased interleukin-2 secretion |
increased interleukin-4 secretion |
increased susceptibility to autoimmune disorder |
increased susceptibility to experimental autoimmune encephalomyelitis |
increased inflammatory response |
liver inflammation |
kidney inflammation |
lung inflammation |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||
| Dusp22tm1Tht/Dusp22tm1Tht | |||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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